在罗马尼亚,疫苗相关性麻痹型脊髓灰质炎的发生率比其他国家高5～17倍。人们早就注意到,在野型脊髓灰质炎病毒感染的潜伏期内进行肌肉注射会增加麻痹性疾病的危险性(此现象称为刺激性脊髓灰质炎)。为此作者在罗马尼亚进行了病例-对照研究,以探索肌肉注射与疫苗相关性脊髓灰质炎之间的关系。 In Romania, the incidence of vaccine-associated paralytic poliomyelitis is 5 to 17 times higher than in other countries. It has long been observed that intramuscular injection during the incubation period of wild-type poliovirus increases the risk of paralytic disease (a phenomenon known as stimulating polio). To this end, the authors conducted a case-control study in Romania to explore the relationship between intramuscular injection and vaccine-associated poliomyelitis.