本文对食管癌高、低发区食管癌患者和正常人,经MNNG诱导的DNA损伤修复功能进行了研究。实验采用外周血淋巴细胞培养的方法。每组又分为对照组及MNNG诱导组。样品以~3H-TdR标记后经液闪仪计数法进行检测。结果发现,低发区正常人经MNNG诱导的DNA损伤修复功能明显高于对照组,两个地区食管癌患者修复能力均低于正常人,与地区无关。 In this paper, the MNNG-induced DNA damage repair function was studied in esophageal cancer patients and normal people with high and low incidence of esophageal cancer. Experiments using peripheral blood lymphocyte culture methods. Each group was divided into control group and MNNG induction group. Samples were labeled with ~3H-TdR and detected by liquid scintillation counting. The results showed that the function of repairing DNA damage induced by MNNG in normal subjects with low incidence area was significantly higher than that in the control group. The repairing ability of esophageal cancer patients in both areas was lower than that in normal subjects and had no relation with the area.