This paper describes the optimization of the impeller having splitters for a turbo blower.Two design variables,chord of splitter and pitch of splitter,are introduced to enhance the blower performance.Blower pressure and ef-ficiency are selected as an object function,and the optimization of the blower impeller is performed by a response surface method (RSM).Three-dimensional Navier-Stokes equations are introduced to analyze the internal flow of the blower and to find the value of the object function for each case.Throughout the shape optimization of the splitters attached to the impeller in the turbo blower,pressure and efficiency at the design flow condition are suc-cessively increased by 5.9 percent and 17.9 percent respectively based on the reference blower.The higher blower efficiency obtained by optimization of impeller having splitters is mainly caused by reducing the number of im-peller blades and optimal design of splitters in the blade passage while pressure increase keeps almost the same with the reference blower.For the object function of pressure,pressure increase is obtained at the design and off-design conditions while efficiency keeps higher compared to the reference blower.The enhancement of blow-er performance is due to the reduction of reverse and circulation flows in the blade passage. This paper describes the optimization of the impeller having splitters for a turbo blower. Two design variables, chord of splitter and pitch of splitter, are introduced to enhance the blower performance. Blower pressure and ef-ficiency are selected as an an object function, and the optimization of the blower impeller is performed by a response surface method (RSM). Three-dimensional Navier-Stokes equations are introduced to analyze the internal flow of the blower and to find the value of the object function for each case.Throughout the shape optimization of the splitters attached to the impeller in the turbo blower, pressure and efficiency at the design flow condition are suc-cessively increased by 5.9 percent and 17.9 percent respectively based on the reference blower. mainly caused by reducing the number of im-peller blades and optimal design of splitters in the blade passage while pressure increase tracking almo for the objective function of pressure, pressure increase is obtained at the design and off-design conditions while efficiency keeps higher than to reference blower. the enhancement of blow-er performance is due to the reduction of reverse and circulation flows in the blade passage.