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目的分析心率震荡(HRT)对包括缺血性心肌病患者发生心源性猝死的预测价值。方法从2008年1～2009年6月就诊的缺血性心肌病患者(ICM)患者中选取符合窦性心率震荡(HRT)分析条件的85名患者,健康对照组31人。根据24h动态心电图(Holter)记录资料,计算HRT的两个参数:震荡初始(TO)和震荡斜率(TS),HRT1组,TO和TS均异常即TO>0%和TS<2.5ms/RR。HRT0组,TO或TS1项异常;终点事件是心源性死亡发生。结果 HRT异常占入选病人总数的28.2%,在445±126的随访时间,11个人死亡,HRT1与年龄、LVEF、TO、TS呈相关性。HRT异常与缺血心肌病患者的死亡率均密切相关。结论 HRT指标与年龄,LVEF等指标有较好的相关性,可作为ICM患者预后指标之一。
Objective To analyze the predictive value of heart rate turbulence (HRT) on sudden cardiac death in patients with ischemic cardiomyopathy. Methods Totally 85 patients with ischemic cardiomyopathy (ICM) from January 2008 to June 2009 were enrolled in this study. The results of HRT analysis included 31 patients and healthy controls. According to 24-hour Holter data, two parameters of HRT were calculated: initial shock (TO) and concussion slope (TS). TOT> 0% and TS <2.5ms / RR were abnormal in HRT1 group. HRT0 group, TO or TS1 abnormalities; end point of cardiac death. Results The abnormality of HRT accounted for 28.2% of the total number of patients selected. At the follow-up time of 445 ± 126, 11 individuals died. The correlation between HRT1 and age, LVEF, TO, TS was found. HRT abnormalities and ischemic cardiomyopathy mortality are closely related. Conclusions There is a good correlation between HRT index and age, LVEF and other indicators, which can be used as one of the prognostic indicators of ICM patients.