染色质中最基本的重复单位就是核小体核心颗粒,它包含147 bp的DNA包绕在中心组蛋白八聚体周围。核小体其实就是一个包装排列布置,即把一段大约长2 m的DNA压缩成只有一个10μm直径的胞核,而且这也是一个动态结构,包含许多细胞过程。比如,核小体能被染色质修饰酶作用而发生翻译后 The most basic repeat unit in chromatin is the nucleosome core particle, which contains 147 bp of DNA surrounding the central histone octamer. Nucleosomes are actually a packaging arrangement that compresses a length of about 2 m of DNA into a single 10 μm diameter nucleus, which is also a dynamic structure that contains many cellular processes. For example, nucleosomes can be posttranslated by chromatin-modifying enzymes