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日本血吸虫病是一种严重危害人类健康的人兽共患寄生虫病,研制疫苗防治该病是当前研究的热点领域。国内外学者对日本血吸虫融合基因疫苗进行了研究,本文综述了该疫苗的构建及其免疫机制等方面的研究新进展。
Japanese schistosomiasis is a zoonotic parasitic disease that seriously endangers human health. To develop a vaccine against this disease is a hot area of current research. Schistosoma japonicum fusion gene vaccine has been studied by domestic and foreign scholars. This paper reviews the recent progress in the construction of the vaccine and its immunological mechanism.