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[目的]分析原发性肝癌患者的个人史和既往史对预后的影响.[方法]回顾性分析535例确诊为原发性肝癌的朝鲜族和汉族患者的相关既往史和个人史资料,随访诊断后的患者生存状态和生存日期,筛选出可能影响肝癌预后的潜在因素进行单因素和多因素分析.[结果]535例患者的1,3年生存率分别为54.0%,22.1%,中位生存时间为31.98个月.单因素分析结果显示,朝鲜族和汉族原发性肝癌患者的1年生存率间差异具有统计学意义(P<0.05),影响1,3年生存率及总生存期的相关因素有年龄、肝炎病史、肝硬化病史、肿瘤分期、肿瘤大小及肝动脉化学治疗栓塞术(TACE)治疗等.多因素分析结果显示,影响肝癌患者总生存期的独立因素包括年龄、肝炎病史、肿瘤分期、肿瘤大小及TACE治疗等.朝鲜族与汉族间存在明显差异的因素有年龄和肝炎病史.[结论]原发性肝癌患者的既往史和个人史对预测其预后具有意义;部分诱发原发性肝癌生成的危险因素对预后未见有显著的影响.
[Objective] To analyze the influence of personal history and past history of patients with primary hepatocellular carcinoma on prognosis. [Methods] A retrospective analysis of 535 cases of Korean and Han patients diagnosed with primary hepatocellular carcinoma related historical and personal history data, follow-up After diagnosis, the survival status and survival date of patients were screened out, and the potential factors that may affect the prognosis of liver cancer were screened out by univariate and multivariate analysis. [Results] The 1- and 3-year survival rates of 535 patients were 54.0% and 22.1% respectively The survival time was 31.98 months.Univariate analysis showed that there was a significant difference in the one-year survival rates between Korean and Han patients with primary liver cancer (P <0.05), and the one and three year survival rates and overall survival Related factors such as age, history of hepatitis, history of cirrhosis, tumor stage, tumor size and TACE, etc. Multivariate analysis showed that independent factors affecting the overall survival of patients with HCC include age, hepatitis History, stage of tumor, size of tumor, TACE treatment, etc. There are significant differences between Korean and Han nationality in history of history of hepatitis and hepatitis.Conclusion: The past history and personal history of patients with primary hepatocellular carcinoma Prognosis is meaningful; some of the risk factors of primary hepatocellular carcinoma induced have no significant effect on prognosis.