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目的:探讨彩色多普勒超声在监测糖尿病患者动脉粥样硬化中的应用。方法:选择2008年1月至2014年12月我院进行颈动脉彩色多普勒超声检查的糖尿病患者和健康志愿者各200例,分别记录双侧颈总动脉内-中膜厚度(Carotid intima-media thickness,c-IMT)及颈总动脉、颈内外动脉斑块发生的情况,同时对不同年龄组糖尿病患者发生颈动脉斑块进行对比分析,比较糖尿病患者与健康志愿者差别。结果:糖尿病患者与健康志愿者比较,颈动脉主干及分支内-中膜厚度厚度明显增加,斑块发生率明显增高,差异均具有统计学意义(P<0.05)。颈动脉斑块发生部位最多见于颈动脉分叉处,达58.2%,而斑块性质以混合性斑块多见,达50.2%。在糖尿病患者中,随年龄增加,患者c-IMT增加,颈动脉斑块发生率亦增高。男性比女性患者c-IMT更高,颈动脉斑块发生率增高。结论:超声在监测糖尿病颈动脉粥样硬化中具有较好临床价值。糖尿病患者颈动脉内-中膜厚度增加,粥样斑块发生率增高,是心血管事件的危险因素。“,”Objective:To evaluate the value of color doppler Ultrasound in patients with type 2 diabetes mellitus for detecting carotid atherosclerosis.MATERIALS AND Methods:200 consecutive patients with newly diagnosed type 2 diabetes mellitus from 2008 January to 2014 December and 200 healthy volunteers were enrolled in our study. Carotid color doppler Ultrasound was applied to measure the carotid intima-media thickness (c-IMT) of common, internal, and external carotid arteries and identify atherosclerotic plaques. Patients with diabetes of different age groups of carotid artery plaques were analyzed. Results:Carotid intima-media thickness and carotid plaque prevalence were significantly increased in diabetic subjects compared to healthy volunteers (P<0.05). The occurrence of carotid artery plaque is most frequently detected in the carotid bifurcation, up to 58.2%, and the mixed plaques are the most common, up to 50.2%. In diabetic patients, c-IMT and carotid artery plaque prevalence increased in male than in female, and also increased with the increase of age.Conclusions:Color doppler ultrasound has significant clinical value in diabetes monitoring in carotid atherosclerosis. The current study shows that carotid artery intima-media thickness and the prevalence of atherosclerotic plaques increased in diabetes mellitus patients, which is associated with cardiovascular risk factors.