新生儿窒息可引起多器官损害，其中肾损害发生率最高。肾损害在超微结构上表现为细胞骨架、细胞极性的改变，从而引起肾小管堵塞，肾损害与能量代谢障碍、 Ｃａ２＋与Ｃａ２＋依赖性蛋白酶、一氧化氮、氧自由基、细胞间粘附分子有关，并可通过一些方法监测。 Neonatal asphyxia can cause multiple organ damage, of which the highest incidence of renal damage. Renal damage appears as a cytoskeleton in the ultrastructure, changes in cell polarity, causing tubular blockage, renal impairment and energy metabolism disorders, Ca2 + and Ca2 + -dependent proteases, nitric oxide, oxygen free radicals, intercellular adhesion Molecular and can be monitored by some means.