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由于老年人的生理学及药代动力学随年龄的增大而改变,特别是老年人一般合并有多种疾患,如高血压、糖尿病、肿瘤等,往往应用的药物品种繁多,使得老年人出现药物不良反应（ADR）的机会增加。一项统计资料表明,60a以上的老年患者用药的ADR发生率为15.4％,老年患者因药物治疗而发生并发症的危险是一般成年人的2.5倍[1]。可见,ADR对老年人的健康危害是十分严重的。我院是北京市老年保健及疾病防治中心,来此就医的老年患者较多。笔者对我院老年人ADR报告进行分析,旨在了解老年人ADR发生趋势,以便为临床老年人合理用药,减少ANR对老年人的危害提供依据。
As the physiology and pharmacokinetics of the elderly change with age, especially the elderly are generally combined with a variety of disorders such as high blood pressure, diabetes, cancer, etc., often used in a wide variety of drugs, making the elderly appear drugs Adverse reaction (ADR) opportunities increase. According to one statistic, the incidence of ADR in elderly patients over 60 years of age is 15.4%, and the risk of complications due to medical treatment in elderly patients is 2.5 times that of the average adult [1]. Visible, ADR on the health hazards of the elderly is very serious. Our hospital is Beijing Geriatric Health and Disease Prevention and Treatment Center, to come to this hospital more elderly patients. The author of our hospital ADR analysis of elderly reports, aimed at understanding the trend of ADR in the elderly in order to rational use of drugs for the elderly to reduce the risk of ANR on the elderly to provide the basis.