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自从一九六三年Reye,Morgan及Baral等氏叙述急性脑病伴有内脏脂肪浸润以来,已引起相当的注意。最近流行病学的资料提示这个综合病征实际上是儿童病毒感染最常见的神经病学并发症之一。自从一九六三年以来,对该病在化学上和组织学上的异常特点已进行了大量的观察,这些观察的结果提示有典型表现时就可迅速作出诊断。目前大多数儿科医生认为一个幼儿患非特异性咽炎、胃肠障碍或流感样疾病后几天出现反复呕吐和意识状态改变者,就可以考虑Reye氏综合征的诊断。对本征的早期辨认和及时的支持治疗能防止昏迷的发生。
Ree, Morgan and Baral et al. Have drawn considerable attention since 1963 when acute encephalopathy was associated with visceral fat infiltration. Recent epidemiological data suggest that this syndrome is actually one of the most common neurological complications of childhood viral infection. Since 1963, a large number of observations have been made on the chemical and histological abnormalities of the disease. The results of these observations suggest that a diagnosis can be promptly made when there is a typical manifestation. At present, most pediatricians consider the diagnosis of Reye’s syndrome in children with recurrent vomiting and altered consciousness after a few days of nonspecific pharyngitis, gastrointestinal disorders, or flu-like illness in a young child. The early identification of the intrinsic and timely supportive treatment can prevent the occurrence of coma.