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在全世界范围内,慢性乙型肝炎病毒(HBV)是引起肝脏疾病的一个主要原因,超过3.5亿人处于持续性HBV感染中,它是导致慢性肝炎发展成为肝硬化、肝细胞肝癌的危险因素〔1〕。HBV感染后形成慢性携带者的几率与受感染时的年龄有关。
Worldwide, chronic hepatitis B virus (HBV) is a major cause of liver disease. Over 350 million people are in persistent HBV infection and are a risk factor for the development of chronic hepatitis into cirrhosis and hepatocellular carcinoma 〔1〕. The chances of developing a chronic carrier after HBV infection are related to the age at the time of infection.