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本文收集了手术切除的胃标本42例,其中包括30例胃癌标本,5例慢性胃溃疡,5例慢性萎缩性胃炎,2例正常(无明显病变的)胃。每例胃标本从病变中心区,病变旁,小弯区和大弯区各取全层(自粘膜至浆膜)胃壁一块,用加以改良的Cajal-Faworsky氏组织块浸银法处理,以显示神经组织,重点观察胃壁内神经组织的轴索有无病变。结果如下: 1.在30例胃癌标本中,有17例在胃癌中心区的神经组织完全消失了;在其余13例胃癌的中心区仍见有少数残留变性的神经组织,其中有4例在癌体的间质内或癌细胞之间出现极少残存的,受损较轻,似是再生的神经轴索,神经组织在癌主体内受损最严重,癌体外围的较轻。 2、在慢性胃溃疡及萎缩性胃炎的病例中,胃壁组织受损较严重区的神经组织受害亦较严重。这样看来,某些慢性胃溃疡和萎缩性胃炎发生癌变,可能与胃神经受损有一定的关系。
This article collected 42 surgically resected gastric specimens, including 30 gastric cancer specimens, 5 chronic gastric ulcers, 5 chronic atrophic gastritis, and 2 normal (no obvious lesions) stomachs. Each gastric sample was taken from the central area of the lesion, the lesion side, the small curve area, and the large curve area to the full-thickness (self-mucosa to serosal) stomach wall and treated with the modified Cajal-Faworsky tissue block silver immersion method to show The nerve tissue focused on the presence or absence of lesions in the axons of nerve tissue in the stomach wall. The results are as follows: 1. Among the 30 gastric cancer specimens, 17 cases had disappeared completely in the central area of the gastric cancer; in the remaining 13 cases of gastric cancer, there were still a few residual degenerated nerve tissues, 4 of which were cancers. Between the body’s mesenchyme or between cancer cells, there is minimal residual, and the damage is lighter. It appears to be a regenerated nerve axons. The nerve tissue is most severely damaged in the cancerous body, and the periphery of the cancerous body is lighter. 2. In the cases of chronic gastric ulcer and atrophic gastritis, the damage to the nerve tissue in the more severely damaged gastric tissue is also serious. It seems that some chronic gastric ulcers and atrophic gastritis have cancerous changes that may have a relationship with gastric nerve damage.