肝硬化病人常有生长激素(GH)基础水平的升高,且对促甲状腺素释放激素(TRH)等促分泌剂有异常反应,原因未明。本文观察一组严重肝硬化患者 GH对生长激素释放激素(GHRH)的分泌反应。选择经临床及实验室检查确诊的肝硬化患者10例,年龄52～71岁,体重61±3kg,以年龄及体重相配的7名作对照组。于早晨清醒、静息状态下进行GHRH 及 TRH 试验。GHRH 试验又分小剂量0.1μg/kg 及大剂量1.0μg/kg 静脉注射两种。在注射 hp GRF- Patients with liver cirrhosis often have elevated basal levels of growth hormone (GH) and have abnormal responses to secretagogues such as thyrotropin-releasing hormone (TRH) for reasons unknown. This article observes a group of patients with severe cirrhosis of GH secretion of growth hormone releasing hormone (GHRH) response. Ten patients with cirrhosis diagnosed by clinical and laboratory tests were selected, aged from 52 to 71 years old and weighing 61 ± 3 kg, with 7 age and weight matched controls. In the morning awake, resting state GHRH and TRH test. GHRH test is divided into small doses of 0.1μg / kg and high-dose 1.0μg / kg intravenous injection of two. After injection of hp GRF-