原发性中枢神经系统淋巴瘤(primary central nervoussystem lymphoma,PCNSL)常见于免疫缺陷患者。近年来其在免疫健全人群中的发病率有所提高,占原发性颅内肿瘤的5%,男女发病比例约为2∶1,多见于成年人,高发年龄为30～65岁。目前对于PCNSL生物学特性的认识仍不完善,淋巴 Primary central nervous system lymphoma (primary central nervous system lymphoma, PCNSL) is common in immunodeficient patients. In recent years, its incidence in immunocompetent populations increased, accounting for 5% of primary intracranial tumors, male and female incidence ratio of about 2: 1, more common in adults, high age of 30 to 65 years old. The current understanding of the biological characteristics of PCNSL is still not perfect, lymphatic