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目的 探讨女性生殖器原发性恶性黑色素瘤的临床特征。方法 对我院收治的 14例女性生殖器的原发性黑色素瘤的临床资料进行回顾性分析。结果 发生于外阴、阴道、宫颈的恶性黑色素瘤分别为 4例、9例、1例。 10例行手术切除辅以化疗和免疫疗法 ,4例单纯行化疗和免疫疗法。 14例中随访 13例。 5例生存期 <1年 ,6例 <2年 ,2例>3年 (其中一例无瘤生存 2 0年 )。结论 女性生殖器的原发性恶性黑色素瘤预后差。其治疗方法以手术为主 ,辅以化疗和免疫治疗的综合治疗。
Objective To investigate the clinical features of female genital primary malignant melanoma. Methods The clinical data of 14 primary female genital melanomas admitted to our hospital were analyzed retrospectively. The results occurred in the vulva, vagina, cervical malignant melanoma were 4 cases, 9 cases, 1 case. Ten patients underwent surgical resection combined with chemotherapy and immunotherapy, and four patients received simple chemotherapy and immunotherapy. Fourteen cases were followed up in 13 cases. Five patients survived <1 year, 6 patients <2 years and 2 patients> 3 years (one of them survived 20 years). Conclusion Female genital primary malignant melanoma has a poor prognosis. The treatment of surgery-based, combined with chemotherapy and immunotherapy combined treatment.