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目的:探讨各类肌炎的病理学特点。方法:对11例患各类肌炎病人的肌肉活检标本进行常规染色、特染、组织酶学染色及超微结构病理研究。结果:11例肌炎病人中感染性肌炎3例,其病理形态表现各具特征。免疫介导性肌炎8例,其病理形态的共同点是坏死肌纤维位于肌束周边,伴灶性炎细胞浸润、小血管壁增厚。结论:苏木精-伊红染色是诊断各种肌炎的主要方法,特染和组织酶学染色对诊断肌炎有辅助作用,电镜下超微结构的观察对包涵体肌炎有诊断价值。
Objective: To explore the pathological features of various myositis. Methods: The muscle biopsy specimens of 11 patients with various types of myositis were routinely stained, stained specially, histologically and ultrastructurally. Results: Three cases of myositis in 11 myositis patients showed pathological features. 8 cases of immune-mediated myositis, the common pathological form of necrotic muscle fibers located in the muscle bundle around with focal inflammatory cell infiltration, small vessel wall thickening. CONCLUSION: Hematoxylin-eosin staining is the main method for the diagnosis of various myositis. The special staining and histological staining may be helpful for the diagnosis of myositis. The observation of ultrastructure by electron microscopy has diagnostic value for inclusion body myositis.