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目的 研究视网膜脱离复位后视网膜超微结构改变,以探讨视功能恢复障碍的机制。方法 12只灰兔通过在视网膜下注射透明质酸钠的方法建立视网膜脱离模型。用透射电镜观察术后 1,2,3,4周的视网膜。结果 视网膜复位早期光感受器外节段缺失、断裂。内节、视细胞核、双极细胞、神经节细胞均可见胞浆水肿,线粒体肿胀和嵴断裂。复位3周后,视网膜细胞结构基本正常,但仍有部分外节变短,神经纤维空洞存在。结论 视网膜复位后不仅光感受器,而且视网膜其他细胞和神经纤维均有不可逆的改变,这些改变导致祝功能恢复不良。
Objective To study the ultrastructural changes of the retina after retinal detachment and reduction to explore the mechanism of visual function recovery disorder. Methods Twelve rabbits were injected retinal subcutaneously with sodium hyaluronate to establish a retinal detachment model. The retina was observed by transmission electron microscopy at 1, 2, 3, 4 weeks after operation. Results Early retinal reattachment outer segment of photoreceptor missing, broken. Intramedullary, visual nuclei, bipolar cells, ganglion cells were visible cytoplasm edema, mitochondria swelling and crista fracture. Three weeks after the reset, the retinal cell structure was basically normal, but some of the outer segments were still shortened, and nerve fiber cavities existed. CONCLUSIONS: Not only photoreceptors, but also irreversible changes of other cells and nerve fibers in the retina after retina reattachment, these changes lead to poor recovery of function.