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目的探讨乳腺癌改良根治术治疗Ⅰ、Ⅱ期乳腺癌的临床疗效。方法收集2006年1月至2009年12月我院收治的110例Ⅰ、Ⅱ期乳腺癌患者资料,采用随机数字表法将患者分为研究组和对照组,各55例,研究组患者采用乳腺癌改良根治术治疗,对照组患者采用经典乳腺癌根治术治疗,随访5年,综合比较两组患者并发症发生率、5年内局部复发、远处转移及生存情况。结果研究组患者并发症发生率为16.4%,低于对照组的32.7%(P<0.05);研究组患者5年内局部复发、远处转移优于对照组(P<0.05),生存率为89.1%,高于对照组的72.7%(P<0.05)。结论乳腺癌改良根治术治疗Ⅰ、Ⅱ期乳腺癌效果确切,可降低并发症,明显改善患者预后。
Objective To investigate the clinical effects of modified radical mastectomy for stage Ⅰ and Ⅱ breast cancer. Methods The data of 110 patients with stage Ⅰ and Ⅱ breast cancer admitted to our hospital from January 2006 to December 2009 were collected. The patients were divided into study group and control group by random number table (55 cases each). The study group was treated with breast The patients in the control group were treated with radical mastectomy. The patients were followed up for 5 years. The incidence of complications, local recurrence, distant metastasis and survival in 5 years were compared. Results The incidence of complication in study group was 16.4%, which was lower than that in control group (32.7%, P <0.05). The recurrence and distant metastasis in study group were better than that in control group (P <0.05) within 5 years and the survival rate was 89.1 %, Higher than 72.7% of the control group (P <0.05). Conclusion Modified radical mastectomy for the treatment of stage Ⅰ, Ⅱ breast cancer with exact effect, can reduce complications and significantly improve the prognosis of patients.