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目的 :研究观察莫西沙星与左氧氟沙星用药治疗下呼吸道感染的疗效及安全性。方法 :选取我院86例下呼吸道细菌感染病患,随机分为莫西沙星组43例(记为观察组),左氧氟沙星43例(记为对照组)。结果 :观察组总有效率为97.67%,显著高于对照组的83.72%,住院时间、喘息消失时间、咳嗽消失时间及体温复常时间均显著少于对照组。上述差异均有统计学意义。但两组不良反应发生率相比较无明显差异,差异无统计学意义。结论 :应用莫西沙星注射剂治疗下呼吸道感染较左氧氟沙星更加适宜,疗效较高。
Objective: To investigate the efficacy and safety of moxifloxacin and levofloxacin in the treatment of lower respiratory tract infection. Methods: Totally 86 patients with lower respiratory tract bacterial infection in our hospital were randomly divided into moxifloxacin group (43 cases) and levofloxacin group (43 cases). Results: The total effective rate in observation group was 97.67%, which was significantly higher than that in control group (83.72%). The hospitalization time, wheezing disappearance time, cough disappearance time and body temperature recovery time were significantly less than those in control group. The above differences were statistically significant. However, there was no significant difference between the two groups in the incidence of adverse reactions, the difference was not statistically significant. Conclusion: Moxifloxacin injection is more suitable for the treatment of lower respiratory tract infection than levofloxacin, with higher efficacy.