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目的了解山东省2006/2007年度(2006年10月~2007年9月)流行性脑脊髓膜炎(流脑)流行病学特征,为预防控制流脑提供依据。方法对网络直报的流脑疫情采用描述流行病学分析及实验室检测。结果山东省2006/2007年度流脑发病34例,发病率0.037/10万,比2005/2006年度(2005年10月~2006年9月)减少45.16%;死亡6例,同比减少40.00%。病例分布在12个设区的市;1~4月病例数占总病例数的65.62%;≤29岁病例数占总病例数的94.11%;在1个市1所学校发生聚集性流脑疫情。在流脑病例中分别检测出A、C群脑膜炎奈瑟菌(Neisseria meningitidis,Nm)1株和3株;在健康人群中检测出A、C群Nm各3株。结论应采取以接种脑膜炎球菌多糖疫苗为主的综合性预防措施,开展流脑病例、健康人群流脑带菌和抗体水平监测。
Objective To understand the epidemiological characteristics of epidemic cerebrospinal meningitis (MCI) in Shandong Province from 2006-2007 (from October 2006 to September 2007), and provide evidence for prevention and control of ECM. Methods Descriptive epidemiological analysis and laboratory tests were used to report the epidemic of meningitis in the network. Results The incidence of meningitis in Shandong Province in 2006/2007 was 34 cases, the incidence was 0.037 / 100 000, which was 45.16% less than that of 2005/2006 (from October 2005 to September 2006); 6 deaths, a decrease of 40.00% compared with the same period of last year. The cases were distributed in 12 districts; the number of cases from January to April accounted for 65.62% of the total number of cases; the number of cases ≤29 years accounted for 94.11% of the total number of cases; in one school in 1 city, . One and three Neisseria meningitidis (Neisseria meningitidis, Nm) strains were detected in the cases of meningitis, and three strains of Nm of group A and C were detected in healthy people. Conclusion Mononuclear meningococcal polysaccharide vaccine-based comprehensive preventive measures should be taken to carry out the epidemic encephalitis cases, healthy people in the streptococcal carriage and antibody levels monitoring.