在本研究中,作者检验了下列假说,即Ⅲ型B族链球菌（GBS）多糖-破伤风类毒素结合菌苗（Ⅲ-TT）的免疫原性和保护效力受3个变量的影响:（1）结合物分子大小;（2）用于偶联的多糖分子大小;（3）多糖与蛋白间的交联程度。 In the present study, the authors examined the hypothesis that the immunogenicity and protective efficacy of Type III Streptococcus group B (GBS) - tetanus toxoid conjugate vaccine (III-TT) are affected by three variables: 1) the molecular size of the conjugate; (2) the size of the polysaccharide molecule used for the conjugation; and (3) the degree of crosslinking between the polysaccharide and the protein.