论文部分内容阅读
目的了解北京市HIV阳性男男性接触者(men who have sex with men,MSM)人群梅毒感染情况,分析其感染梅毒的相关因素。方法对2011年4月到2013年3月北京市报告的HIV阳性MSM的血样进行快速血浆反应素试验(RPR)及梅毒颗粒凝集试验(TPPA),结合“艾滋病综合防治数据信息管理系统”的病例报告数据进行分析,分析方法有χ2检验、单因素logistic回归等。结果 2011年4月~2013年3月,北京市报告HIV阳性MSM 2 633例,RPR及TPPA阳性者348例,梅毒感染率13.22%;其中HIV感染者梅毒感染率13.10%(334/2 550),AIDS患者梅毒感染率16.87%(14/83);报告前3个月无保护性行为比例为65.48%(990/1 512);HIV阳性MSM感染梅毒特点为:曾患性病者(29.19%)高于未患性病者,40岁以上者(17.65%)高于年轻者,样本来源为性病门诊者(16.80%)高于其他,低文化程度者(16.54%)高于高文化程度者,传染病医院报告者(15.37%)高于其他机构,CD4计数较高者(15.04%)高于较低者。结论北京市HIV阳性MSM的梅毒感染率较高,应根据感染梅毒的特征进行筛查及规范治疗,降低其对HIV传播的促进作用。
Objective To understand the prevalence of syphilis in HIV-positive men who have sex with men (MSM) in Beijing and analyze the related factors of syphilis infection. Methods Rapid plasma reactive element assay (RPR) and syphilis particle agglutination test (TPPA) were performed on the blood samples of HIV positive MSM reported from Beijing from April 2011 to March 2013, and combined with the “AIDS Integrated Data Management Information System” Of cases reported data analysis, analysis methods χ2 test, one-way logistic regression. Results From April 2011 to March 2013, Beijing reported 633 cases of HIV-positive MSM, 348 cases of RPR and TPPA positive, and syphilis infection rate of 13.22%. Among them, the infection rate of syphilis in HIV-infected persons was 13.10% (334/2 550) , Syphilis infection rate in AIDS patients was 16.87% (14/83), 65.48% (990/1 512) in the first 3 months. Syphilis infection in HIV-positive MSM patients was 29.19% (17.65%) were higher than those younger than those who were not suffering from sexually transmitted diseases. The sample source was STD clinic (16.80%) higher than other people, and those with low education level (16.54%) were higher than those with high education level Hospitalized reporters (15.37%) were higher than other institutions, with higher CD4 count (15.04%) than the lower ones. Conclusion The prevalence of syphilis in HIV-positive MSM in Beijing is relatively high. Screening and standardized treatment should be based on the characteristics of syphilis infection and its promotion effect on HIV transmission should be reduced.