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本组五例病毒性心肌炎并发三度房室传导阻滞均经心电图证实发病前均有上呼吸道感染症状,用阿托品、异丙肾上腺素及营养心肌等药物治疗无效.后给予静脉滴注琥珀酰氢化考的松500mg 或600mg/d,共7~10天,改用地塞米松口服维持,取得较好效果.随访6~24个月无复发,恢复正常生活和工作(详见附表).讨论导致三度房室传导阻滞的病因较多,本组5例患者均系青年,抗“O”正常,缺乏风湿热的其他证据.结合临床考虑为病毒性心肌炎所致.病毒性心肌炎的急性期多数学者不主张用激素。其理由是激素通过延迟蛋白合成而抑制干扰素的合成和释放,导致机体防御能力下降加速病
The group of five cases of viral myocarditis complicated with third-degree atrioventricular block were confirmed by electrocardiogram before the onset of symptoms of upper respiratory tract infection with atropine, isoproterenol and nutritional myocardium and other drugs ineffective after intravenous infusion of succinyl Hydrocortisone 500mg or 600mg / d, a total of 7 to 10 days, switch to oral administration of dexamethasone, and achieved good results. Follow-up of 6 to 24 months without recurrence, return to normal life and work (see schedule). Discussed the cause of the third degree atrioventricular block more etiology, 5 patients in this group are young, anti “O” normal, lack of other evidence of rheumatic fever combined with clinical considerations for viral myocarditis caused by viral myocarditis Most scholars do not advocate the use of hormones in acute phase. The reason is that hormones inhibit the synthesis and release of interferon by delaying protein synthesis, leading to a decrease in the defense ability of the body to be accelerated