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目的探讨高脂肥胖大鼠的制备方法及其应用意义。方法采用高脂饮食饲养 SD大鼠，观察其体重增长和体重 Lee’s指数的变化。结果高脂饮食饲养的大鼠体重及 Lees指数明显大于正常饲料组。结论高脂饮食可导致大鼠肥胖并可作为人类肥胖研究的良好模型。
Objective To investigate the preparation method of fat-bearing obese rats and its significance. Methods SD rats were fed with high fat diet to observe the change of body weight and Lee’s index. Results The body weight and Lees index of rats fed with high-fat diet were significantly higher than those of normal diet. Conclusion High-fat diet can lead to obesity in rats and can be used as a good model for the study of human obesity.