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小细胞肺癌是一种高度恶性的肿瘤,在生物学和临床上与其他主要组织类型的肺癌不同,它具有更强烈的肿瘤细胞增殖能力,并倾向于早期局部浸润和广泛的播散转移,但是它对化学治疗和放射治疗比较敏感。已经表明,肿瘤细胞DNA含量分析可以作为肿瘤病人预后的指征。Blondal及其同事在本报告中分析研究了小细胞肺癌病人的生存是否与核内DNA频率分布图型有关,
Small cell lung cancer is a highly malignant tumor. It is biologically and clinically different from other major tissue types of lung cancer. It has a stronger tumor cell proliferation ability, and tends to localized early infiltration and extensive disseminated metastasis, but It is sensitive to chemotherapy and radiation therapy. It has been shown that the analysis of tumor cell DNA content can serve as an indication of the prognosis of tumor patients. In this report, Blondal and colleagues analyzed whether the survival of patients with small cell lung cancer is related to patterns of nuclear DNA frequency distribution.