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目的癌性胸水是恶性肿瘤晚期常见并发症，研究如何较好地控制胸水而又减少治疗次数及疗效较好的药物。方法采用胸穿套管针建立闭式引流，在胸水基本流净、肺复张基础上予以吡柔比星４０ｍｇ；白介素－Ⅱ４０万单位作胸腔内灌注一次性疗程。结果总有效率９１．６６％（１１／１２），毒副作用３８．５℃以下发热者９１．６６％，轻度胸痛３３．３３％，食欲不振６６．６６％。结论研究认为该方法能达到较好疗效，毒副作用较轻，为病人容易接受的治疗方法。
Objective Cancer pleural effusion is a common complication of advanced malignant tumors. It is to study how to better control the pleural effusion and reduce the number of treatment and better efficacy of the drug. Methods The thoracic trocar was used to establish a closed drainage, and pirarubicin 40 mg was given on the basis of the basic flow of pleural effusion and lung recanalization. Interleukin-II 400,000 units were used as a one-time treatment for intrathoracic infusion. Results The total effective rate was 91.66% (11/12). The toxic and side effects were 31.6°C fever, 91.66% fever, 33.33% mild chest pain, and 66.66% loss of appetite. Conclusions The study concluded that this method can achieve better curative effect with less toxic side effects and is an easily accepted treatment method for patients.