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目的调查有和无重叠症状的肠易激综合征(IBS)患者的生活质量、精神心理状况,分析有重叠症状IBS患者生活质量特点,探讨影响其生活质量的主要因素及重叠症状产生的可能原因。方法对2007年10月至2008年4月在我院消化科门诊就诊的、符合罗马Ⅲ诊断标准的76例IBS患者建立健康档案,采用消化道症状调查表、汉化版简明健康调查量表(SF-36)、焦虑自评量表(SAS)和抑郁自评量表(SDS)进行问卷调查。根据问卷调查结果将其分为有重叠症状组(食管、胃、十二指肠和肛门直肠症状)和无重叠症状组,分析比较两组患者生活质量和精神心理状况,并对结果进行统计学分析。结果有重叠症状组IBS患者生活质量较无重叠症状组降低,合并焦虑抑郁状态的比例高于无重叠症状组(P<0.05)。结论伴随重叠症状的IBS患者生活质量受到影响,不良精神心理因素可能是其生活质量主要影响因素及重叠症状产生的原因。
Objective To investigate the quality of life and mental status of patients with irritable bowel syndrome (IBS) with and without overlapping symptoms and to analyze the quality of life of patients with IBS with overlapping symptoms and to explore the main factors influencing their quality of life and the possible causes of overlapping symptoms . Methods A total of 76 patients with IBS who met the diagnostic criteria of Rome Ⅲ from October 2007 to April 2008 were enrolled in the digestive department outpatient department of our hospital to establish a health file. The digestive tract symptom questionnaire, Chinese version concise health survey scale (SF -36), anxiety self-rating scale (SAS) and depression self-rating scale (SDS). According to the results of the questionnaire, the patients were divided into overlapping symptoms (esophageal, gastric, duodenal and anorectal symptoms) and non-overlapping symptoms. The quality of life and mental and psychological conditions were compared between the two groups, and the results were statistically analyzed analysis. Results The quality of life of IBS patients with overlapping symptoms was lower than that without overlapping symptoms, and the proportion of patients with anxiety and depression was higher than those without symptoms (P <0.05). Conclusions The quality of life of IBS patients with overlapping symptoms is affected. The adverse mental and psychological factors may be the main influencing factors of their quality of life and the causes of overlapping symptoms.