概况:左旋咪唑(Levamisole LMS)是四咪唑(Tetramisole又名驱虫净)的一种左族对映异构体。1966年首次人工合成后作为一种广谱驱虫剂应用于临床。1971年Renoux氏偶然发现LMS对小鼠有刺激免疫,增强抗感染能力的作用,从而引起人们的极大关注并开始对它进行多方面的研究。结果表明,LMS可通过恢复吞噬细胞、T细胞功能等细胞免疫途径而修 General: Levamisole LMS is a group of enantiomers of tetraimidazole (Tetramisole, also known as anthelmintic). After being artificially synthesized for the first time in 1966, it was used as a broad spectrum insect repellent for clinical use. In 1971, Renoux accidentally discovered that LMS stimulates immunity in mice and enhances anti-infective ability, which has caused people’s great concern and began to conduct various researches on it. The results show that LMS can be repaired by restoring cellular immune pathways such as phagocytes and T cell functions.