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本文对34例急性肾炎患儿测定补体成份 C_(1q)、C_4、C_3、B、C_5及 C_9的血清值。结果显示:急性肾炎患儿血清补体成份血清水平变化以 C_3最为显著,C_4、C_9须连续测定才能发现,C_(1q)、C_5、B 变化不大。患儿 ASO(+)者,经典途径、替代途径均可活化,但“原发性”活化同时只能有一条;C_3值降低程度大。血清补体成份含量不随激活反应呈数学式变化,单纯测定某些补体成份血清值特别是对活化途径判断意义不大,检测其降解产物可能会有帮助。
In this paper, serum levels of C_ (1q), C_4, C_3, B, C_5 and C_9 were determined in 34 children with acute nephritis. The results showed that serum C_3 of children with acute nephritis had the most significant change of C_3, C_4 and C_9 must be measured continuously, C_ (1q), C_5 and B did not change much. Children with ASO (+), the classic pathway, alternative pathway can be activated, but “primary” activation can only have one; C_3 value decreased. Serum complement component does not change with the activation reaction was a mathematical change, a simple determination of certain serum values of complement components, especially to determine the activation path is not meaningful, the detection of its degradation products may be helpful.