论文部分内容阅读
目的:观察吉诺通在慢性鼻窦炎、鼻息肉内镜手术围手术期应用对术后术腔恢复的影响。方法:将167例接受功能性鼻内镜手术治疗的慢性鼻窦炎、鼻息肉患者随机分为吉诺通组(84例)和对照组(83例),两组接受相同的手术治疗及术前、术后常规处理。吉诺通组口服吉诺通胶囊,术前300mg/次,每日3次,连续4~7d;术后第3天开始服用300mg/次,每日3次,连续6~8周。对照组不服用吉诺通胶囊。两组患者于术后1、2、3、4、6、8、12周行内镜检查,记录术腔情况。结果:吉诺通组术后1~2周术腔清洁情况优于对照组,差异有统计学意义(P<0.01);吉诺通组术后1~12周上皮化情况优于对照组,差异有统计学意义(P<0.05)。结论:内镜鼻窦手术围手术期使用吉诺通有助于加快术后黏膜恢复,提高手术疗效;吉诺通是目前较为理想的内镜鼻窦手术围手术期的辅助用药。
OBJECTIVE: To observe the effect of Gynolone on the postoperative recovery of the operative cavity after perioperative application of endoscopic sinus surgery and chronic nasosinusitis. Methods: A total of 167 patients with chronic sinusitis and nasal polyposis treated with functional endoscopic sinus surgery were randomly divided into geinuron group (n = 84) and control group (n = 83). Both groups received the same operation and preoperative , After conventional treatment. Jinuo Tong group oral Ginomatto capsules, preoperative 300mg / time, 3 times a day for 4 to 7d; the first 3 days after taking 300mg / times, 3 times a day for 6 to 8 weeks. The control group did not take Ginolone capsules. Two groups of patients at end of 1,2,3,4,6,8,12 postoperative endoscopy, recording the surgical cavity. Results: The cleanliness of the lumen was better than that of the control group at 1 ~ 2 weeks postoperatively (P <0.01). The skin epithelialization of the Guinotong group was superior to that of the control group at 1 ~ 12 weeks postoperatively, The difference was statistically significant (P <0.05). CONCLUSION: Perioperative use of Ginobon in endoscopic sinus surgery can help to speed up postoperative mucosal recovery and improve the curative effect. Ginohexyl is an ideal perioperative adjuvant for endoscopic sinus surgery.