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目的:探讨三维适形放疗应用于中晚期食管癌的近期疗效。方法:中晚期食管癌64例根据入院顺序分为治疗组与对照组各32例,2组都采用放射治疗,治疗组选择三维适形放疗,对照组选择进行普通放疗,都连续治疗2个月。结果:治疗组的肺部放射损伤发生率为3.1%,对照组为21.9%,组间对比差异有统计学意义(P<0.05)。随访1年,治疗组的生存率为93.8%,对照组的生存率为68.8%,治疗组的生存率明显高于对照组(P<0.05)。结论:三维适形放疗应用于中晚期食管癌能有效减少放射损伤,同时提高近期1年生存率,值得推广应用。
Objective: To investigate the short-term effect of three-dimensional conformal radiotherapy on advanced esophageal cancer. Methods: 64 cases of advanced esophageal cancer were divided into treatment group and control group according to admission order, 32 cases in each group. Radiotherapy was used in both groups. Three-dimensional conformal radiotherapy was used in the treatment group and normal radiotherapy was selected in the control group. All patients were treated continuously for 2 months . Results: The incidence of lung injury was 3.1% in the treatment group and 21.9% in the control group. The difference between the two groups was statistically significant (P <0.05). The follow-up of 1 year, the survival rate of the treatment group was 93.8%, the survival rate of the control group was 68.8%, the survival rate was significantly higher in the treatment group (P <0.05). Conclusion: Three-dimensional conformal radiotherapy for advanced esophageal cancer can effectively reduce radiation injury, while improving the 1-year survival rate in the near future, it is worth to promote the application.