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目的 :测定 c- myc和 c- fos基因在肾照射 2 4h后的表达情况 ,确定该表达与肾晚期辐射损伤之间是否相关。方法 :实验采用了 15周龄、雌性 C3H/ He Slc小鼠作为研究对象 ,线性加速器 ML - 2 0 MDX产生 4MV X射线 ,以约1.0 Gy/ m in的剂量率进行左肾单侧照射 ,总剂量分别为 9、12
OBJECTIVE: To determine the expression of c-myc and c-fos gene in the kidney after irradiation for 24 hours and determine whether the expression correlates with radiation damage in the late stage of kidney. Methods: 15 - week - old female C3H / He Slc mice were used as experimental subjects. The linear accelerator ML - 20 MDX was used to generate 4 MV X - rays. Unilateral irradiation of the left kidney with a dose rate of 1.0 Gy / The doses were 9,12