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梗塞净CH由川芎、赤芍、桃仁等中药组成,为治疗缺血性脑血管疾病的复方注射液。实验结果表明:梗塞净CH具有显著的抗ADP胶原诱导的血小板聚集作用,具有量效关系,在一定的范围内,随药物浓度的增大,抑制作用增强。药物浓度的对数值与抑制聚集的百分数的相关关系极好,其直线回归方程有较高的可靠性,用其预测是准确的。用直线回归方程求得以(ADP)和胶原为诱导剂的抑制50%的浓
Infarct net CH is composed of traditional Chinese medicine such as Chuanxiong, Radix paeoniae, peach kernel and so on. It is a compound injection for the treatment of ischemic cerebrovascular disease. The experimental results show that the infarct net CH has a significant anti-ADP collagen-induced platelet aggregation with a dose-effect relationship, and within a certain range, with the increase of drug concentration, the inhibitory effect is enhanced. The correlation between the logarithm of the drug concentration and the percentage of inhibition of aggregation is excellent, and the linear regression equation has higher reliability, and its prediction is accurate. Using a linear regression equation to obtain 50% inhibition of (ADP) and collagen as inducers