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21例原发性高血压用心痛定治疗,每次10～20mg,一天三次口服达一周。所有病人的血压都有下降,收缩压降低的幅度是30.67±14.23mmHg,而舒张压是16.67±10.70mmHg。于8时、12时和晚6时相继服用心痛定,而每天在早7时,下午4时测量血压,即分别为服药后13和4小时测血压,比较其下降幅度,两次检查的血压下降幅度无显著差异(P>0.05)。因此,认为心痛定一天三次服用是合理的,因为它可以在24小时内维持血压在正常水平。当停用心痛定一周,血压又都回升到治疗前的高水平。副作用极轻微,且能忍受。因此建议心痛定作为一种有效、简便、接近理想的抗高血压药物来使用。
21 cases of essential hypertension with nifedipine treatment, each 10 ~ 20mg, oral once a day for up to one week. All patients had a decrease in blood pressure, with a decrease in systolic blood pressure of 30.67 ± 14.23 mmHg and a diastolic pressure of 16.67 ± 10.70 mmHg. At 8:00, 12:00 and 6:00 after taking nifedipine, and daily at 7 am, 4 pm to measure blood pressure, that is, respectively, 13 and 4 hours after taking medication to measure blood pressure, compared with the decline, the two check blood pressure There was no significant difference (P> 0.05). Therefore, it is reasonable to assume that nausea is prescribed three times daily because it maintains normal blood pressure within 24 hours. When stopping heartburn for a week, blood pressure has risen to a high level before treatment. Side effects are minimal and can be tolerated. Therefore recommended nifedipine as an effective, easy, close to the ideal antihypertensive drugs to use.