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目的探讨恶性肿瘤生存者癌痛治疗与生存质量的关系。方法对入选患者给予三阶梯止痛治疗,应用数字评分疼痛分级法及EORTC QLQ-C30问卷调查表分别对止痛治疗前后患者进行疼痛测定及生活质量测定,对结果进行比较分析。结果 (1)使用三阶梯止痛治疗后,中度疼痛缓解率为95.3%,重度疼痛缓解率为85.3%,疼痛总缓解率为88.4%;不良反应主要表现为恶心、呕吐、便秘等。(2)按照三阶梯止痛疗法疼痛治疗后患者生活质量较好,中、重度癌痛患者社会功能、情绪功能、躯体功能、失眠、整体质量均明显改善(P<0.01);中度疼痛患者生活质量得分为65.49±8.54,重度疼痛患者生活质量得分33.38±10.67,与治疗前比较差异均有统计学意义(P<0.01)。结论三阶梯止痛疗法能明显缓解癌性疼痛,有效地提高恶性肿瘤生存者的生活质量。
Objective To investigate the relationship between cancer pain treatment and quality of life in cancer survivors. Methods Three-step analgesic treatment was given to the selected patients. The pain scores and the quality of life of the patients before and after pain-relieving were measured by the digital grading pain score method and the EORTC QLQ-C30 questionnaire respectively. The results were compared and analyzed. Results (1) The pain relief rate was 95.3%, the pain relief rate was 85.3% and the pain relief rate was 88.4%. The main adverse reactions were nausea, vomiting and constipation. (2) According to the three-step analgesic therapy, the quality of life of patients with pain was better, and the social function, emotional function, body function, insomnia and overall quality of patients with moderate and severe cancer pain were significantly improved (P <0.01) The quality score was 65.49 ± 8.54, and the quality of life score of severe pain patients was 33.38 ± 10.67, which was significantly different from that before treatment (P <0.01). Conclusion Three-step analgesic therapy can significantly relieve cancer pain and effectively improve the quality of life of cancer survivors.