论文部分内容阅读
目的探讨盐酸乌拉地尔注射液联合甲钴胺治疗妊娠期高血压疾病的效果。方法选取复旦大学附属中山医院青浦分院2014年1月-2016年1月住院患者100例作为研究对象,以抽签法随机分为观察组与对照组各50例,2组患者均接受常规治疗,对照组患者在常规治疗的基础上进行硫酸镁微量静脉泵入方式治疗,观察组患者在常规治疗的基础上进行盐酸乌拉地尔注射液联合甲钴胺治疗,对比两组患者治疗前后血压、心率变化以及新生儿Apgar评分和并发症发生情况。结果两组患者治疗后的血压和心率指标均明显低于治疗前,而且治疗后观察组的血压和心率指标均明显低于对照组,差异具有统计学意义(P<0.05);观察组新生儿Apgar评分8~10分比例、并发症发生率与对照组比较,差异有统计学意义(P<0.05)。结论盐酸乌拉地尔注射液结合甲钴胺可稳定妊娠期高血压患者心率及血压,改善Apgar评分并降低并发症。
Objective To investigate the effect of urapidil hydrochloride combined with mecobalamin in the treatment of hypertensive disorder complicating pregnancy. Methods 100 cases of inpatients from January 2014 to January 2016 in Qingpu Branch of Zhongshan Hospital Affiliated to Fudan University were enrolled in this study. The patients were randomly divided into observation group (50 cases) and control group (50 cases) by random selection. The patients in both groups received routine treatment. The patients in the group were treated by micro-venous injection of magnesium sulfate on the basis of routine treatment. The patients in the observation group were treated with urapidil hydrochloride combined with mecobalamin on the basis of routine treatment. The changes of blood pressure and heart rate before and after treatment were compared between the two groups As well as neonatal Apgar scores and complications. Results After treatment, the blood pressure and heart rate index of the two groups were significantly lower than those before treatment. After treatment, the blood pressure and heart rate of the observation group were significantly lower than those of the control group (P <0.05) Apgar score of 8 to 10 points, the incidence of complications compared with the control group, the difference was statistically significant (P <0.05). Conclusion Urapidil hydrochloride combined with mecobalamin can stabilize the heart rate and blood pressure of hypertensive patients with gestational hypertension, improve the Apgar score and reduce the complications.