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γ-连环素 (γ- catenin,γ- cat)是实质细胞粘附连接处钙粘附素 (cadherin,cd) /连环素复合体的胞内组成部分 ,同时还是桥粒的组成成份之一。近来发现 ,γ- cat同时还是一种癌基因 ,并参与 wnt信号传导通路 ,介导粘附连接与桥粒之间的交流等。本文对 γ- cat的生物学特性及其功能作一综述
γ-catenin (γ-cat) is an intracellular component of the cadherin (cd) / catenin complex at the junction of parenchymal cells and is also one of the components of desmosomes. Recently, it has been found that γ-cat is also an oncogene and participates in the wnt signaling pathway to mediate the exchange between adhesion junctions and desmosomes. This article reviews the biological characteristics and functions of γ-cat