冠心病(CHD)是现代社会严重威胁人类健康的主要疾病之一,其病死率极高。内皮细胞的损伤与CHD的发生发展关系密切。血管内皮祖细胞(endothelial progenitor cells,EPCs)作为内皮细胞的前体细胞,在组织缺血及血管损伤时动员入血,参与微血管的生成及血管内皮的修复,在冠心病发生及 Coronary heart disease (CHD) is one of the major diseases that pose a serious threat to human health in modern society and its mortality rate is extremely high. Endothelial cell damage and the occurrence and development of CHD are closely related. As the precursor cells of endothelial cells, endothelial progenitor cells (EPCs) mobilize into the blood during tissue ischemia and vascular injury, participate in the formation of microvessels and the repair of vascular endothelium. In the pathogenesis of coronary heart disease