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目的评估河南省居民膳食中黄曲霉毒素B1的暴露量,估算膳食中黄曲霉毒素B1暴露所引发的肝癌发生风险。方法 2013-2014年对河南省部分食品中黄曲霉毒素开展了监测,结合2002年河南省居民营养与健康状况调查中食物摄入量数据,利用点评估的方法对居民膳食中黄曲霉毒素B1暴露水平进行评估。结果总人群中黄曲霉毒素B1膳食暴露量为2.32 ng/(kg·bw·d),农村居民为2.76 ng/(kg·bw·d),城市居民为1.40 ng/(kg·bw·d);膳食中对黄曲霉毒素B1暴露量贡献率较高的食品为小麦粉及其制品(82.42%)和植物油(13.10%);膳食中黄曲霉毒素B1导致肝癌发生风险在总人群中为0.09/10万人,农村居民中为2.76/10万人,城市居民中为0.05/10万人。结论河南省农村地区人群中黄曲霉毒素B1暴露风险较高,小麦粉及其制品、植物油是河南省人群最主要的黄曲霉毒素B1膳食暴露来源。
Objective To evaluate the exposure of aflatoxin B1 to the diet of residents in Henan Province and estimate the risk of liver cancer caused by the aflatoxin B1 exposure in the diet. Methods Aflatoxins in some foods in Henan Province were monitored during 2013-2014. According to the food intake data of Henan Province in 2002, the method of point assessment was used to detect aflatoxin B1 in residents’ diet Level assessment. Results The total aflatoxin B1 dietary exposure was 2.32 ng / (kg · bw · d) in the general population, 2.76 ng / (kg · bw · d) in rural residents and 1.40 ng / (kg · bw · d) ; The foods with the highest contribution to the aflatoxin B1 exposure were wheat flour and its products (82.42%) and vegetable oil (13.10%); the aflatoxin B1 dietary risk of liver cancer in the general population was 0.09 / 10 The number of rural residents is 2.76 per 100,000 and that of urban residents is 0.05 per 100,000. Conclusion There is a high risk of aflatoxin B1 exposure in rural areas of Henan Province. Wheat flour and its products and vegetable oils are the main sources of aflatoxin B1 diet in Henan province.