目的探讨重症脑卒中并发中枢性休克的机制、临床特点及预后。方法选择我院2004年12月—2011年12月发病24h内入院的脑卒中患者45例,按照是否并发中枢性休克分为休克组15例,非休克组30例。比较两组患者的病灶部位、脑卒中类型及临床疗效。结果休克组脑干和丘脑卒中发生率高于非休克组,休克组脑出血发生率高于非休克组,休克组存活率低于非休克组,差异均有统计学意义(P<0.05)。结论脑干、丘脑部位的脑出血易并发中枢性休克,中枢性休克预后差。 Objective To investigate the mechanism, clinical characteristics and prognosis of severe stroke complicated by central shock. Methods Forty-five stroke patients admitted to our hospital from December 2004 to December 2011 were divided into shock group (n = 15) and non-shock group (n = 30) according to whether they were complicated by central shock. The lesion location, stroke type and clinical effect were compared between the two groups. Results The incidence of brain stem and thalamic stroke in shock group was higher than that in non - shock group. The incidence of cerebral hemorrhage in shock group was higher than that in non - shock group. The survival rate in shock group was lower than that in non - shock group. The difference was statistically significant (P <0.05). Conclusions Cerebral hemorrhage in the brainstem and thalamus is prone to central shock and the prognosis of central shock is poor.