Due to a series of linear projects built along National Highway 214, the second“Permafrost Engineering Corridor”on the Qinghai-Tibet Plateau has formed. In this paper, by overcoming the problems of data decentralization and standard inconsistency, permafrost characteristics and changes along the engineering corridor are systematically summarized based on the survey and monitoring data. The results show that:1) Being controlled by elevation, the permafrost is dis-tributed in flake discontinuity with mountains as the center along the line. The total length of the road section in per-mafrost regions is 365 km, of which the total length of the permafrost section of National Highway 214 is 216.7 km, and the total length of the permafrost section of Gong-Yu Expressway is 197.3 km. The mean annual ground tempera-ture (MAGT) is higher than-1.5 °C, and permafrost with MAGT lower than-1.5 °C is only distributed in the sections at Bayan Har Mountain and E'la Mountain. There are obvious differences in the distribution of ground ice in the differ-ent sections along the engineering corridor. The sections with high ice content are mainly located in Zuimatan, Duo-gerong Plain and the top of north and south slope of Bayan Har Mountain. The permafrost thickness is controlled by the ground temperature, and permafrost thickness increases with the decrease of the ground temperature, with the change rate of about 37 m/°C. 2) Local factors (topography, landform, vegetation and lithology) affect the degradation process of permafrost, and then affect the distribution, ground temperature, thickness and ice content of permafrost. Asphalt pavement has greatly changed the heat exchange balance of the original ground, resulting in serious degrada-tion of the permafrost. Due to the influence of roadbed direction trend, the phenomenon of shady-sunny slope is very significant in most sections along the line. The warming range of permafrost under the roadbed is gradually smaller with the increase of depth, so the thawing settlement of the shallow section with high ice-content permafrost is more significant.