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半枝莲水煎剂灌胃给药,对正常大鼠的体温无明显影响,对皮下注射10%干酵母混悬液10ml·kg~(-1)引起发热大鼠有明显的解热作用,并有明显的剂量依赖关系.药后1小时体温开始下降.给药组大鼠发热时程明显缩短.
Scutellaria barbata water decoction administered intragastrically had no significant effect on the body temperature of normal rats. The subcutaneous injection of 10% dry yeast suspension (10 ml·kg-1) caused significant antipyretic effects in rats with fever. There was a significant dose-dependent relationship. The body temperature began to decline after 1 hour. The duration of fever in the administration group was significantly shortened.