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研究了用固体碱KF/Al2O3为缚酸剂,DMF为溶剂,以卤代烃为烷基化剂实现1,2,3-苯并三唑N-烷基化反应.不同的卤代烃,得到不同比例N1及N2烷基化产物,烷基化产率在57%~95%之间.
The N, N-alkylation of 1,2,3-benzotriazole with solid base KF / Al2O3 as acid-binding agent, DMF as solvent and halogenated hydrocarbon as alkylating agent were studied. Different halogenated hydrocarbons, obtained in different proportions of N1 and N2 alkylation products, alkylation yield between 57% ~ 95%.