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英国South Wales地区作无脑儿、脊椎裂的研究时,发现许多病人均未作母血清甲胎蛋白检查。第一次产前检查时的孕周,对中断先天性畸形儿妊娠很重要。因此作了七个医院的调查。16周前来作产前检查占52.5%,19周前占78.9%,16～18周第一次来产前检查占26.4%,此时为最好的普查甲胎蛋白的时间。分析未来产前检查的原因有:妊娠的确诊是由一般医生占73%,由产科医生占17%,其它组织确诊9%。2/3病人确诊妊娠后立即转来医院产前检查。分析18周后首次产前检查的原因,主要为虽一般医生建议来检查但被延误占32.5%,
In a study of anencephalic and spina bifida in the South Wales region of the United Kingdom, many patients were not tested for maternal serum alpha-fetoprotein. The gestational age at the time of the first prenatal examination is important to interrupt the pregnancy of congenital malformations. So made a survey of seven hospitals. The prenatal diagnosis was 52.5% at 16 weeks, 78.9% at 19 weeks, and the first prenatal examination at 16-18 weeks was 26.4%. This was the best time to censor a-fetoprotein. The reasons for the analysis of future antenatal examinations are as follows: The diagnosis of pregnancy was made by 73% of general practitioners, 17% by obstetricians and 9% by other organizations. Two-thirds of patients diagnosed with pregnancy immediately transferred to the hospital for prenatal care. Analysis of the reasons for the first prenatal examination after 18 weeks was mainly due to the delay of 32.5%