糖尿病勃起功能障碍研究进展

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阴茎勃起功能障碍是糖尿病常见的并发症,其发生与多种病理生理机制相关,如糖基化终末产物、氧自由基、NO合成障碍、内皮素及其受体、上调的RhoA/Rho激酶途径、神经病变等。治疗较为困难且需要多种模式,如口服药物、阴茎内药物注射、尿道内栓剂、真空勃起装置、阴茎内假体等。 Erectile dysfunction is a common complication of diabetes mellitus, which occurs with a variety of pathophysiological mechanisms such as advanced glycation end products, oxygen free radicals, NO synthesis disorders, endothelin and its receptors, upregulated RhoA / Rho kinase Way, neuropathy and so on. Treatment is more difficult and requires a variety of modes, such as oral drugs, intra-penile drug injection, intraurethral suppository, vacuum erection, penile prosthesis.
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