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【作用特点】本品为广谱利福霉素类半合成抗菌素,对革兰氏阳性和革兰氏阴性菌、病毒均有抑制作用,对结核杆菌在0.5微克/毫升浓度即有作用,在极低浓度时(0.01～0.05微克/毫升),对葡萄球菌、链球菌、肺炎双球菌、枯草杆菌、流感杆菌均较敏感,对大肠杆菌、布鲁氏杆菌需要高浓度才有作用。结核杆菌对甲哌力复霉素也能产生耐药性,但与其他抗结核药物尚未发现有交叉耐药性;与四环素、氯霉素、红霉素、苄青霉素等抗菌素也未出现有交叉耐药性。
【Features】 This product is a broad-spectrum rifamycins semi-synthetic antibiotics, against Gram-positive and Gram-negative bacteria, viruses have an inhibitory effect on Mycobacterium tuberculosis at a concentration of 0.5 micrograms / ml has a role in the Very low concentrations (0.01 ~ 0.05 μg / ml), Staphylococcus aureus, Streptococcus, Streptococcus pneumoniae, Bacillus subtilis, influenza bacilli are more sensitive to Escherichia coli, Brucella need high concentrations have a role. Mycobacterium tuberculosis metronidazole can also produce drug resistance, but with other anti-TB drugs have not been found cross-resistance; and tetracycline, chloramphenicol, erythromycin, benzylpenicillin and other antibiotics did not appear to cross Resistance.