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目的比较单纯使用丙泊酚和丙泊酚复合小剂量芬太尼在无痛人工流产中的临床效果和安全性、经济性。方法选择2007年7~10月自愿行无痛人工流产的患者156例,随机分为丙泊酚组(A组)和丙泊酚复合芬太尼组(B组)。B组于丙泊酚给药前予以芬太尼1μg/kg缓慢静脉推注,两组患者丙泊酚的静脉推注剂量均为2~2.5 mg/kg。待麻醉效果满意后开始手术。结果B组麻醉镇痛效果优75例,占96.1%;良3例,占3.9%;有效率为100%。A组麻醉镇痛效果优43例,占55.1%;良24例,占30.8%;差11例,占14.1%;有效率为85.9%。两组之间比较差异有统计学意义(P<0.05)。结论丙泊酚复合小剂量芬太尼应用于无痛人工流产较单纯使用丙泊酚效果优且不良反应少,安全可靠,经济实用的麻醉方法。
Objective To compare the clinical effects, safety and economy of fentanyl with propofol and small dose of propofol in painless artificial abortion. Methods A total of 156 patients with voluptuous painless abortion from July to October 2007 were randomly divided into propofol group (group A) and propofol combined fentanyl group (group B). Group B was given a bolus injection of fentanyl 1μg / kg before propofol administration. Intravenous bolus doses of propofol were 2 ~ 2.5 mg / kg in both groups. To be satisfied with the anesthetic effect after surgery. Results The anesthesia analgesic effect in group B was excellent in 75 cases (96.1%), good in 3 cases (3.9%) and effective rate (100%). A group of anesthesia analgesic effect was excellent in 43 cases, accounting for 55.1%; good in 24 cases, accounting for 30.8%; poor in 11 cases, accounting for 14.1%; the effective rate was 85.9%. The difference between the two groups was statistically significant (P <0.05). Conclusion Propofol combined with low dose of fentanyl in analgesic induced abortion is superior to propofol alone, with less adverse reactions, safe and reliable, economical and practical anesthesia.