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已知动脉粥样硬化斑块的主要细胞成份是平滑肌细胞,电镜下已观察过穿过内弹性膜至内膜的中膜平滑肌细胞。Benditt等认为斑块细胞是一种突变了的平滑肌细胞,并在黑种女人动脉斑块的葡糖—6—磷酸脱氢酶(G6PD)的同功酶电泳中,发现斑块组织可能是由单个平滑肌细胞突变增生而成的。因此了解动脉中膜平滑肌的生物学特性是近代研究动脉粥样硬化斑块生成的重要课题之一。本文参照Ross等采用组织培养方法,繁
The major cellular component of atherosclerotic plaques is known to be smooth muscle cells, which have been observed under the electron microscope to mediate smooth muscle cells lining the tunica intima. Benditt, etc. that plaque cells is a mutant smooth muscle cells, and in black women arterial plaque glucose-6-phosphate dehydrogenase (G6PD) isozymatic electrophoresis found that plaque tissue may be caused by A single smooth muscle cell mutation derived from. Therefore, to understand the biological characteristics of arterial mesangial smooth muscle is one of the important topics in the study of atherosclerotic plaque in modern times. In this paper, Ross and other organizations using tissue culture methods