1　病例资料女,26岁。因少尿、水肿、黄疸2天入院。入院前2天,病人因头皮外伤经青霉素皮试阴性后,静脉滴注青霉素G钠盐960万单位,数小时后出现全身皮肤搔痒、红色斑丘疹,伴腰痛、少尿(100ml/d),尿呈酱油色,皮肤粘膜黄染,逐渐出现颜面及双下肢水肿。无畏寒发热、尿频、尿急,在 1 case information Female, 26 years old. Due to oliguria, edema, jaundice 2 days admission. Two days prior to admission, the patient was scalded with penicillin G sodium salt 9.6 million units by scalp trauma due to scalp injury. A few hours later, systemic skin itching, red rash, low back pain, oliguria (100 ml / day) Urine was soy sauce color, yellow skin mucosa, and gradually appear face and lower extremity edema. Fearless fever, frequent urination, urgency, in